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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46a424a6155378f676f807bc9fb9179fc4e6822832f28d4d57146c2c2d622c39' 
  AND token = '9z2VBfHMoQcjmEEtwIrT58rRSS2iGFVZHy+BTN5lUdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}