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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28f79c65b5a2aa99f6d288beb1fc86ced148555a0f07fe4d86ea6d84fabe45af' 
  AND token = 'D6r+gw598PBas2Ukw8NFuLUenyePxJ53vxhGrqMwr/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}