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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e818396a2d3fb2f83a5da4cc3f3f45d784584df7a57c5ec397f0e6681dd8049' 
  AND token = 'rhACaUbngS5V2F+oOw0kdfVPL540ub0gmfThuvCM/1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}