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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b3a342db82fc1e0f195ea2a3b33380e7a1de320947e8827d295cb8af042ed08' 
  AND token = '15cSpckmxY2Km9Av1T3DeRmF7Um6yINBPyUq2UY8/2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}