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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84e86ddf20889705b2d93905934aa5046853f68a14cba41ed3d2054708551c21' 
  AND token = 'XQCV6MaFR6Y6zR3STAs19EOqHbJe55eP7uO1e+OYZ5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}