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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70d111b1bcb1c0e5648ad3e7ada45d4f659529635e548d1010c6f3265b72fd50' 
  AND token = 'AdGlrSPRufcHlYEcGsdnBpOtip8kX5uFs+PYCW6xBcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}