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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e2270517c035dd4b6bcc1ba56f5265ece2e1007eb033eb1bafd47218480e5cf' 
  AND token = 'NE6Qhux+LnUCktusgbrmQIgX02VWK2MQGeJQ/AsylnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}