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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af040b078c424a1da1e32e99a44e6f3b467322780b40790f2776f5a6e6c61818' 
  AND token = '/GvVGgvk2Faq5csH/R2qektT+wUpcpl2xv6XqI4oKPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}