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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f96edb300c77076acd026a34f002149c85c0f505e7d287e77e85a037b61a633' 
  AND token = 'JAy0e50OiXQ3+jPVw6mQYLSwT8ut+ZyCAT8A80IX8QM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}