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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e4378b296d3f64918c4333fd1751f7f6e90d49d192b819cc71766b78169133f' 
  AND token = 'wndzJiH4PFz+yiSNQaspY1fuEN98mbY+nrvJkS5RJzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}