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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01c0ec8836a1a4adeb158f9c7f0156e83577d08624e1340cbade3ce2149db98f' 
  AND token = 'lAxP6vMljmp3ymyqK0BnCnDuTEXjcc5ObxmdTFliqUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}