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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '500568b921e2c2bc5351f9d9edc88f651980b484d518cdf00036728a687b79cf' 
  AND token = 'o2agfTlbOrKO24sUABmJ5PdJa/lXBAD1tYATn5O1/9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}