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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ae9cc8827d552630b16449612e9308df5d60d024d82f367b86b617a5f435014' 
  AND token = 'Lig6atWn3+/QfUhsnTkKyx+RKlHSRg0WfYfFJ6ZlYs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}