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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1194ac477e9090a14ad3debbed4fad6671f0d00444064f18f1e55a772ed0b571' 
  AND token = 'YTr7r0B/tXaI8wM6T2n+gMzPsiRE+L07E1NthCxK7iQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}