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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff39814d9b4ba280c6fc30e74a3b2cd0405403b04369c0beaf8a58b5298fce1a' 
  AND token = 'GUTm1B+U6XfnxFbyBluBIPMdwhNq5h0axZwdGRKn0x4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}