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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42c456d9a883f65fd98e75c71110635664096ca9c091c91e9e0392f961e424bb' 
  AND token = 'PKpMkv1BNSigzW3Qcj1X68BHtT3aVez0ZO2ZvYXPjsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}