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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f820494dac58a1476a10bdeae6fc0ca6e48113223a8c1f70ffd12f3850b8167d' 
  AND token = 'Lj3lUeMFxtPgozq8BikeVYS7/wEoHyW5rv9xAA2rwEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}