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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16af1d8fbbf614f00ac8a451d909fa234b5a2afe325fd599b55ac59b55b8519a' 
  AND token = 'uD5fe8IBvxEKEz7CKpP/9Q91f8JaN3Unh+OjCh9RV7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}