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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c24ae5a0b92c214bfbdf31b641fade21cfa343d17fc2514d33e03b8fe97f99fb' 
  AND token = 'i4cIoGq/LRpt4MNOCCLrdwUF0v9snN4CmtMFup8U9ok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}