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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dec8aec2fb7c6ab6c16e1e2c4b0081b461e12f5278128479f5160be2ab81f1d' 
  AND token = 'OD7UfXCcCv9dw6BkNj8rtivrF1kzpA+AjvLeWmGGS+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}