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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39fbd40e684befefa44c61a577f89aae890fd4a919618fa60624a453aa8b4b6c' 
  AND token = 'WHRDh8RnpwTxn/jY6stuYd5cd84D/n3aySi0Ne68Hdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}