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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ee2b199c04913d58915e925c61e929eaa401a96531a3a95de0035871881c88b' 
  AND token = 'X3vLm0KppiRxXO8XBXwaNlqPediqSiGnbRL5dP45RWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}