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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78ead05c0f8c7dd47e87a79226474eeaa6f0a0fe135c7f0a5269986442a295ff' 
  AND token = 'Su+5iLog0qNto58PNfKkfobSKo65cCAeklS1n2S8TUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}