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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2750d3ff2622f937de0635b1a8a37774fd4ee51384e4cdf3cd80e9da377adcf8' 
  AND token = 'zY87HOxf2XV1E+pn9gGqdVRaYNW9LKXBsiXPgpasCRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}