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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bfc4a23f706a961ab6333c300e5298fe6baf4476189d449146c9667e70153aa' 
  AND token = '8f608xitnlYd/avSova+KLlNg2zMOaURszWUUwZM/18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}