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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d2087d5c98f188adfcd2c1713b759e274325bbf2574cae8ddc735b8a8c6993f' 
  AND token = 'K6fzGCZ81MWZoQAK0h2jPH2XXLfay1Zb6ExUctiZrU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}