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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c4054cf2d47ab0e0e450af12bdad9bd589ce3e75595b1030e9f2efc1e572f22' 
  AND token = 'eAmkzLGcqgDUP14vlF4VI2vF0bQ6x6gASnm2YF2XNVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}