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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46a27dfe7cd73f76049824fc739195f6d59f027f3b38a6af2274f88689c893e8' 
  AND token = 'h8ajz5os2Yf7C/uMUHU6MgkwjjGal3D+dszqIyODzSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}