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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c68ddbe48a3b292039f1182bf11a1f9e508354b26a6aa6fcb9f215b5baca8bc' 
  AND token = '0uIScvGs856BhzPZ3UcW0u7jq18ncFKf3zMlGuY9gTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}