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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13e27c4306678290176afc7b51629414bec4e7d1c1da026f51950017dc616fdd' 
  AND token = 'jS7WY48Qw6TpQRxdW3YJVDdPgNwDbHi+vchDHiPQD14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}