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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21196e5c4ee5880d6dba6ab539d30b0270509c5a1a9738f9321ddd11eb514b64' 
  AND token = 'iu/yMnn3eg3tIUcpBAu+bious0ekFCeoBYOu5lZlE0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}