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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7500d7d944d56bc5497eadbd1d06def93b56ffeee5044daaf638327d2850731' 
  AND token = 'e/r671IG2SBqW6lDwt5PTHyCy/Qlk5zmVY3vaCzGAm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}