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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20d7b66b2bdf50af88ab3252cad5a2674ec769b18cef54dacb1fb5ac92cfdafb' 
  AND token = 'AstudRq0PrkfB24l4pzvqsKq41Lr6n4NSsz4f9Rc2X8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}