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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '680314386427eeb5b3be46ae51fa6e1570fae0df22a76814d52b9cc482af9995' 
  AND token = '02NWrWBaz9tnb+3+aBlIA9W2aOjwQojb4cvF4EciorI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}