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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a20fd1f2c052672bd8cb61f285f84caf3dcbeb6054304c865a01c1f47b1c6b42' 
  AND token = 'CX+z6lZtWCuAWJK8aTqRdE8p+bm/OcTRtyyX72w/EJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}