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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f322e8258f0c6f8e400d6716e5ba5f799a8db2d49b5876de8dd5b0e2706587c7' 
  AND token = 'E09lF3ca1+mxS+NxIg8jYUEREFIGM2YlzQ89aTqUeRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}