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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebfc08508ad3f74266812db1e3a3126ed914f8ad3bc2004ca6bc14e0cc1a71a2' 
  AND token = 'LMpl+30lEDK320Iuz9QaXLUYcaWDXDM0oMpnO7AbM7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}