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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6e72d52781c6fd2759f6a352dfe0df6606ee352e33c2b5152281afcde46dbf4' 
  AND token = '1nRiM0CGq7s+N1OKPYDSLCrqK79zKGGDq1sBEgmALTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}