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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01b91a7a9db139dc42aec6d5fda0df3bb0c5d20c58adc58f109ad608327b7186' 
  AND token = 'p4VjJv4YTjW7tH8GIJAUdDPIJl87iAYZr6gLeYRyNNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}