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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a03eb4e01ceeae0d1d043443fe9708c233dcb0a94a5226d7c63a325df101056' 
  AND token = 'Ll3dCliUr9aYP3QB88XFnsBAfx4wHajfA0EjN1Wnwjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}