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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f53b5d8b02a93d5223b8be41c13b42d100489ba0adc099697db27626700aaac3' 
  AND token = 'jQG9Gy/YXaOjChPnljT1idTFl1qcGS7IKKmFeoyR018=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}