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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1e2f02cb2209f9d17a6e9186ede8b7e0d026454db91c1da0325662536754fab' 
  AND token = 'x/azcOsCq15gXbin+VEDqt7hlGiZKkrtQFKAAQiOtDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}