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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65a490589e423e94017642d249025f952b6de26838582dc4b63e789b9ca78e2e' 
  AND token = 'aaz0ApwjOGQbeoOaau0reG5SLOS0+kPj/k1LQR9nx6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}