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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '041268b5c4e26016abab589e452920bc2b612599b9e1c4b9e21545e165f40dfd' 
  AND token = '24E97j/3UrnvOzPdrt6L0gNZtv5xsZD2RFWofE1mQk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}