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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '394e2febcd9244e7553df387cc452dfc072b8b13c391ed7c87a9da7f6aa1d2f5' 
  AND token = 'mS2u0jIFCRe0K6E8TBG4PLQWBzlBj+26B1y609OSRbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}