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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01f3f4286782f8e90e9bedf349f75a97d3e502592f187f414447a51412a92848' 
  AND token = 'bCIHDWHORt1lGd/O2vWdggh7wdEexb0m3bk+olUz5xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}