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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '384b002c7b5694d0ca023e438e092c25f8fda8e340851986de4c7da3085c7241' 
  AND token = '5EG1KVTsv64BfW+xfYUbj0ZXYD8nEiVSrmEheOKrLL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}