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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '377154190465084ee84ecd51cfd77ccf6a35d0f822cb2bf3db699751eabf447a' 
  AND token = 'ukxNDcGp7T4WYjMv44G1ymPRNmzdRBarOqUwOlfzZAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}