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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '427d98149d082437da78485b250ac8d6f743995ac6709d9c8d078d214294030f' 
  AND token = 'm7YCCqbi2ywjaTKaVT25XRY5lazA64F0KvXX8AryyJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}