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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4eb554b21bf61b8da5e51f68453e9b31e12190dfe58b2f00b74327c0a153c93' 
  AND token = '/roYe5c9Q1p1hX4K2/oQlnlswjS4RKANnMZeg8Y2UBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}